Infliximab and nephrotic syndrome.
نویسندگان
چکیده
Infliximab is a chimeric tumor necrosis factor-alpha (TNF-alpha) monoclonal antibody, which has been used extensively in patients with rheumatoid arthritis and inflammatory bowel disease. It also appears to be effective in other conditions such as psoriasis and ankylosing spondylitis. The major side effect of infliximab is infection. Renal complications are uncommon and not well recognized. This report describes a probable case of infliximab-induced membranous nephropathy.
منابع مشابه
A case report on nephrotic syndrome associated with ankylosing spondylitis effectively treated with infliximab.
Renal abnormalities have been reported to occur in patients with ankylosing spondylitis (AS). This study examined a patient who suffered from AS for two years. The 24-hour urine protein of the patient was 4.80 g/day. The result of renal biopsy showed minimal change. The patient was treated with infliximab. After two months, nephrotic syndrome was treated successfully.
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عنوان ژورنال:
- Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
دوره 20 12 شماره
صفحات -
تاریخ انتشار 2005